Gender Differences in Neural Decision-Making: Cognitive Mechanisms, Educational Implications, and the Role of AI

Authors

Keywords:

educational implications, cognitive mechanisms, gender differences, decision-making, emotional processing, cultural influences, fMRI, EEG, MEG, artificial intelligence, targeted advertising

Abstract

This narrative review synthesises evidence on gender-specific neurocognitive mechanisms underlying decision-making, emotional processing, and learning, and examines how AI-driven analyses can enhance personalised interventions. Drawing on EEG, fMRI, MEG, ERP, and eye-tracking studies, we show that women preferentially engage medial prefrontal and limbic networks, during semantic-relational and emotional tasks, whereas men recruit parietal-occipital circuits for visuospatial processing. Cultural context further shapes these patterns. AI applications, such as machine learning classifiers on neurophysiological data, improve the accuracy of gender-informed predictions, and support adaptive, neurodiversity-aware pedagogies. We conclude that integrating neuroscientific and AI insights can inform gender-sensitive educational design and decision-support systems, provided ethical safeguards against algorithmic bias and privacy breaches are in place. 

Author Biographies

  • Ioannis Mavroudis, Leeds Teaching Hospitals NHS Trust, UK & Aristotle University of Thessaloniki, Greece

    Department of Neuroscience
    Leeds Teaching Hospitals NHS Trust, UK
    Third Department of Neurology
    Aristotle University of Thessaloniki, Greece

  • Foivos Petridis, Aristotle University of Thessaloniki, Greece

    Third Department of Neurology
    Aristotle University of Thessaloniki, Greece

  • Alin Ciobica, Alexandru Ioan Cuza University of Iasi, Romania

    Faculty of Biology
    Alexandru Ioan Cuza University of Iasi, Romania
    Ioan Hăulică Institute of Apollonia University of Iasi, Romania
    CENEMED Platform for Interdisciplinary Research
    Grigore T. Popa University of Medicine and Pharmacy of Iasi, Romania
    Academy of Romanian Scientists, Iasi Branch, Romania

  • Gabriel Dascalescu, Alexandru Ioan Cuza University of Iași, Romania

    Faculty of Biology
    Alexandru Ioan Cuza University of Iași, Romania
    Ioan Hăulică Institute of Apollonia University of Iași, Romania

  • Dimitrios Kazis, Aristotle University of Thessaloniki, Greece

    Third Department of Neurology
    Aristotle University of Thessaloniki, Greece

  • Antoneta Dacia Petroaie, University of Medicine and Pharmacy Grigore T. Popa, Iasi, Romania

    Faculty of Medicine
    University of Medicine and Pharmacy Grigore T. Popa, Iasi, Romania

  • Otilia Novac, University of Medicine and Pharmacy Grigore T. Popa, Iasi, Romania

    Faculty of Medicine
    University of Medicine and Pharmacy Grigore T. Popa, Iasi, Romania

  • Ioana Vata, Apollonia University, Iași, Romania

    Apollonia University, Iași, Romania

  • Bogdan Novac, University of Medicine and Pharmacy Grigore T. Popa, Iasi, Romania

    Faculty of Medicine
    University of Medicine and Pharmacy Grigore T. Popa, Iasi, Romania

Published

2025-09-08

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